Metallothionein-1 suppresses rheumatoid arthritis pathogenesis by shifting the Th17/Treg balance
Author:
Affiliation:
1. Institute of Biological Therapy; Shenzhen University; Shenzhen China
2. Department of Immunology; Shenzhen University School of Medicine; Shenzhen China
3. Department of Laboratory Medicine; Peking University Shenzhen Hospital; Shenzhen China
Funder
Technology Development Project of Shenzhen Science and Technology Innovation Committee
Basic Research Project of Shenzhen Science and Technology Innovation Committee
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201747151/fullpdf
Reference54 articles.
1. Cytokines in the pathogenesis of rheumatoid arthritis;McInnes;Nat. Rev. Immunol.,2007
2. Role of cytokines in rheumatoid arthritis;Feldmann;Annu. Rev. Immunol.,1996
3. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages;Harrington;Nat. Immunol.,2005
4. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines;Fossiez;J. Exp. Med.,1996
5. Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion;Lubberts;Arthritis Rheum.,2004
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