TMP778, a selective inhibitor of RORγt, suppresses experimental autoimmune uveitis development, but affects both Th17 and Th1 cell populations-Reference-Cited by-同舟云学术

TMP778, a selective inhibitor of RORγt, suppresses experimental autoimmune uveitis development, but affects both Th17 and Th1 cell populations

Published:2018-10-09 Issue:11 Volume:48 Page:1810-1816
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Lyu Cancan¹²,Bing So Jin¹,Wandu Wambui S.¹,Xu Biying¹,Shi Guangpu¹,Hinshaw Samuel J.¹,Lobera Mercedes³,Caspi Rachel R.¹,Lu Lin²,Yang Jianfei³,Gery Igal¹^ORCID

Affiliation:

1. Laboratory of Immunology; National Eye Institute; National Institutes of Health; Bethesda MD USA

2. State Key Laboratory of Ophthalmology; Zhongshan Ophthalmic Center; Sun Yat-Sen University; Guangzhou China

3. GlaxoSmithKline; Cambridge MA USA

Funder

Intramural Program of the National Eye Institute (NEI)

National Institutes of Health

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201747029/fullpdf

Reference27 articles.

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2. Role of Th1 and Th17 cells in organ-specific autoimmunity;Dardalhon;J. Autoimmun.,2008

3. IL-17 and Th17 cells;Korn;Annu. Rev. Immunol.,2009

4. Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category;Luger;J. Exp. Med.,2008

5. Th17 cells in inflammation and autoimmunity;Singh;Autoimmun. Rev.,2014

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