Quantification of highly selective sigma-1 receptor antagonist CM304 using liquid chromatography tandem mass spectrometry and its application to a pre-clinical pharmacokinetic study

Author:

Avery Bonnie A.1ORCID,Vuppala Pradeep K.1,Jamalapuram Seshulatha1,Sharma Abhisheak1,Mesangeau Christophe2,Chin Frederick T.3,McCurdy Christopher R.2

Affiliation:

1. Department of Pharmaceutics and Drug Delivery, School of Pharmacy; The University of Mississippi; University MS 38677 USA

2. Department of BioMolecular Sciences, School of Pharmacy; The University of Mississippi; University MS 38677 USA

3. Department of Radiology; Stanford University; Stanford CA 94305 USA

Funder

National Institute on Drug Abuse

National Institute of General Medical Sciences

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Reference31 articles.

1. The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog;Martin;J. Pharmacol. Exp. Ther.,1976

2. A steric theory of opioid agonists, antagonists, agonist-antagonists, and partial agonists;Martin;NIDA Res. Monogr.,1984

3. Autoradiographic localization of sigma receptor binding sites in guinea pig and rat central nervous system with (+)3H-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine;Gundlach;J. Neurosci.,1986

4. Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling;Hellewell;Eur. J. Pharmacol.,1994

5. A proposal for the classification of sigma binding sites;Quirion;Trends Pharmacol. Sci.,1992

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3