1. Department of Respiratory Medicine, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan
2. Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences Sojo University Kumamoto Japan
3. Department of Medical Information Sciences and Administration Planning Kumamoto University Hospital Kumamoto Japan
4. Laboratory of Stem Cell and Neuro‐Vascular Biology, Genetics and Developmental Biology Center, National Heart, Lung, and Blood Institute National Institutes of Health Bethesda Maryland USA