Pharmacokinetic drug-drug interaction assessment of LCZ696 (an angiotensin receptor neprilysin inhibitor) with omeprazole, metformin or levonorgestrel-ethinyl estradiol in healthy subjects-Reference-Cited by-同舟云学术

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Pharmacokinetic drug-drug interaction assessment of LCZ696 (an angiotensin receptor neprilysin inhibitor) with omeprazole, metformin or levonorgestrel-ethinyl estradiol in healthy subjects

Published:2015-11-04 Issue:1 Volume:5 Page:27-39
ISSN:2160-763X
Container-title:Clinical Pharmacology in Drug Development
language:en
Short-container-title:

Author:

Gan Lu¹,Jiang Xuemin²,Mendonza Anisha¹,Swan Therese¹,Reynolds Christine²,Nguyen Joanne²,Pal Parasar³,Neelakantham Srikanth³,Dahlke Marion⁴,Langenickel Thomas⁴,Rajman Iris⁴,Akahori Mizuki⁵,Zhou Wei²,Rebello Sam²,Sunkara Gangadhar²

Affiliation:

1. Novartis Institutes for BioMedical Research; Cambridge MA USA

2. Novartis Institutes for BioMedical Research; East Hanover NJ USA

3. Novartis Healthcare Pvt Ltd; Hyderabad Andhra Pradesh India

4. Novartis Institutes for BioMedical Research; Basel Switzerland

5. Novartis Pharma K.K; Tokyo Japan

Funder

Novartis Pharma

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpdd.181/fullpdf

Reference31 articles.

1. LCZ696: A dual-acting sodium supramolecular complex;Feng;Tetrahedron Letters,2012

2. Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi);Gu;J Clin Pharmacol,2010

3. Dual neurohormonal intervention in CV disease: Angiotensin receptor and Neprilysin inhibition;Segura;Expert Opin Investig Drugs,2013

4. Neutral endopeptidase inhibition, the natriuretic peptide system: An evolving strategy in cardiovascular therapeutics;Mangiafico;Eur Heart J,2013

5. Novel roles of nuclear angiotensin receptors and signaling mechanisms;Gwathmey;Am J Physiol Regul Integr Comp Physiol,2012

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