Magnetic resonance imaging–guided phase 1 trial of putaminal AADC gene therapy for Parkinson's disease-Reference-Cited by-同舟云学术

Magnetic resonance imaging–guided phase 1 trial of putaminal AADC gene therapy for Parkinson's disease

Published:2019-03-26 Issue:5 Volume:85 Page:704-714
ISSN:0364-5134
Container-title:Annals of Neurology
language:en
Short-container-title:Ann Neurol

Author:

Christine Chadwick W.¹,Bankiewicz Krystof S.²,Van Laar Amber D.³,Richardson R. Mark⁴,Ravina Bernard⁵,Kells Adrian P.⁵,Boot Brendon⁵,Martin Alastair J.⁶,Nutt John⁷,Thompson Marin E.²,Larson Paul S.²

Affiliation:

1. Department of NeurologyUniversity of California San Francisco

2. Department of Neurological SurgeryUniversity of California San Francisco

3. Department of NeurologyUniversity of Pittsburgh

4. Department of Neurological SurgeryUniversity of Pittsburgh

5. Voyager Therapeutics, Inc.

6. Department of Radiology and Biomedical ImagingUniversity of California San Francisco

7. Department of NeurologyOregon Health Sciences University

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ana.25450

Reference28 articles.

1. Levodopa and the Progression of Parkinson's Disease

2. Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease

3. Depletion of AADC activity in caudate nucleus and putamen of Parkinson’s disease patients; implications for ongoing AAV2-AADC gene therapy trial

4. Pharmacokinetic and Pharmacodynamic Changes During the First Four Years of Levodopa Treatment in Parkinson’s Disease

5. Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, pragmatic randomised trial

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