Plasminogen activator inhibitor‐1 augments damage by impairing fibrinolysis after traumatic brain injury

Author:

Griemert Eva‐Verena1,Schwarzmaier Susanne M.2,Hummel Regina1,Gölz Christina1,Yang Dong1,Neuhaus Winfried3,Burek Malgorzata4,Förster Carola Y.4,Petkovic Ivan1,Trabold Raimund5,Plesnila Nikolaus6,Engelhard Kristin1,Schäfer Michael K.17,Thal Serge C.17ORCID

Affiliation:

1. Department of AnesthesiologyUniversity Medical Center of Johannes‐Gutenberg‐University Mainz Mainz Germany

2. Department of AnesthesiologyLudwig‐Maximilians‐University (LMU) Munich Medical Center Munich Germany

3. Austrian Institute of Technology, Department Health and EnvironmentMolecular Diagnostics Vienna Austria

4. Department of Anesthesia and Critical CareUniversity of Würzburg Würzburg Germany

5. Institute for Surgical Research at the Walter Brendel Center of Experimental MedicineUniversity of Munich Medical Center Munich Germany

6. Institute for Stroke and Dementia Research (ISD)Ludwig‐Maximilians‐University (LMU) Munich Medical Center, Munich, Germany and Munich Cluster for Systems Neurology (Synergy) Munich Germany

7. Focus Program Translational NeuroscienceUniversity Medical Center of Johannes‐Gutenberg‐University Mainz Mainz Germany

Funder

Johannes Gutenberg-Universität Mainz

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Reference58 articles.

1. The International Incidence of Traumatic Brain Injury: A Systematic Review and Meta-Analysis

2. Mechanisms of brain injury;Gennarelli TA;J Emerg Med,1993

3. Early post‐traumatic cerebral blood flow mapping: correlation with structural damage after focal injury;Bullock R;Acta Neurochir Suppl (Wien),1992

4. Microthrombi formation after severe head trauma

5. Early Microvascular and Neuronal Consequences of Traumatic Brain Injury: A Light and Electron Microscopic Study in Rats

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