Concise Review: Challenging the Pluripotency of Human Testis-Derived ESC-like Cells-Reference-Cited by-同舟云学术

Concise Review: Challenging the Pluripotency of Human Testis-Derived ESC-like Cells

Published:2011-07-26 Issue:8 Volume:29 Page:1165-1169
ISSN:1066-5099
Container-title:Stem Cells
language:en
Short-container-title:

Author:

Tapia Natalia¹,Araúzo-Bravo Marcos J.¹,Ko Kinarm²³,Schöler Hans R.¹⁴

Affiliation:

1. Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany

2. Center for Stem Cell Research, Institute of Biomedical Science and Technology, Konkuk University, Seoul, Republic of Korea

3. Department of Neuroscience, School of Medicine, Konkuk University, Seoul, Republic of Korea

4. Faculty of Medicine, University of Münster, Münster, Germany

Abstract

Abstract Several research groups have claimed to have successfully generated pluripotent or multipotent cells from human testis. However, the pluripotent character of those cells with respect to gene expression profile and ability to generate teratomas has been called into question. Here, we critically review these reports and provide insight to guide future studies on the derivation of human pluripotent cells from testicular tissue.

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Developmental Biology,Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/stem.669

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