Matuzumab and cetuximab activate the epidermal growth factor receptor but fail to trigger downstream signaling by Akt or Erk

Author:

Yoshida Takeshi,Okamoto Isamu,Okabe Takafumi,Iwasa Tsutomu,Satoh Taroh,Nishio Kazuto,Fukuoka Masahiro,Nakagawa Kazuhiko

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference51 articles.

1. Receptors for epidermal growth factor and other polypeptide mitogens;Carpenter;Annu Rev Biochem,1987

2. Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors;Klapper;Adv Cancer Res,2000

3. Autocrine interaction between TGF α and the EGF-receptor: quantitative requirements for induction of the malignant phenotype;Di Marco;Oncogene,1989

4. Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers;Gullick;Br Med Bull,1991

5. Epidermal growth factor-related peptides and their receptors in human malignancies;Salomon;Crit Rev Oncol Hematol,1995

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