Pathogenic Mutation of ALK2 Inhibits Induced Pluripotent Stem Cell Reprogramming and Maintenance: Mechanisms of Reprogramming and Strategy for Drug Identification-Reference-Cited by-同舟云学术

Pathogenic Mutation of ALK2 Inhibits Induced Pluripotent Stem Cell Reprogramming and Maintenance: Mechanisms of Reprogramming and Strategy for Drug Identification

Published:2012-10-22 Issue:11 Volume:30 Page:2437-2449
ISSN:1066-5099
Container-title:STEM CELLS
language:en
Short-container-title:STEM CELLS

Author:

Hamasaki Makoto¹,Hashizume Yoshinobu²,Yamada Yoshinori¹,Katayama Tomohiko¹,Hohjoh Hirohiko³,Fusaki Noemi⁴,Nakashima Yasuharu⁵,Furuya Hirokazu⁶,Haga Nobuhiko⁷,Takami Yoichiro¹,Era Takumi¹

Affiliation:

1. Department of Cell Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, 2‐2‐1 Honjo, Kumamoto, Japan

2. RIKEN Program for Drug Discovery and Medical Technology Platforms, 2‐1 Hirosawa, Wako, Saitama, Japan

3. Department of Molecular Pharmacology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4‐4‐1 Ogawahigashi, Kodaira, Tokyo, Japan

4. DNAVEC Corporation, 6 Ookubo, Tsukuba, Ibaragi, Japan

5. Department of Orthopaedic Surgery, Kyushu University School of Medicine, 3‐1‐1 Maedashi, Higashi‐ku, Fukuoka, Japan

6. Department of Neurology, Neuro‐Muscular Center, National Omuta Hospital, 1044‐1 Tachibana, Omuta, Fukuoka, Japan

7. Rehabilitation Medicine, Graduate School of Medicine, The University of Tokyo, 7‐3‐1 Hongo, Bunkyo‐ku, Tokyo, Japan

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Developmental Biology,Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/stem.1221

Reference49 articles.

1. Investigations of Activated ACVR1/ALK2, a Bone Morphogenetic Protein Type I Receptor, That Causes Fibrodysplasia Ossificans Progressiva

2. Insights from a rare genetic disorder of extra-skeletal bone formation, fibrodysplasia ossificans progressiva (FOP)

3. Constitutively Activated ALK2 and Increased SMAD1/5 Cooperatively Induce Bone Morphogenetic Protein Signaling in Fibrodysplasia Ossificans Progressiva

4. Dysregulated BMP Signaling and Enhanced Osteogenic Differentiation of Connective Tissue Progenitor Cells From Patients With Fibrodysplasia Ossificans Progressiva (FOP)

5. Dysregulation of the BMP-p38 MAPK Signaling Pathway in Cells From Patients With Fibrodysplasia Ossificans Progressiva (FOP)

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