Control of translation by eukaryotic mRNA transcript leaders—Insights from high‐throughput assays and computational modeling
Author:
Affiliation:
1. Department of Biological Sciences Carnegie Mellon University Pittsburgh Pennsylvania USA
2. Computational Biology Department Carnegie Mellon University Pittsburgh Pennsylvania USA
Funder
National Institute of General Medical Sciences
Publisher
Wiley
Subject
Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/wrna.1623
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1. Translational Control under Stress: Reshaping the Translatome
2. Elaborate uORF/IRES features control expression and localization of human glycyl-tRNA synthetase
3. TASEP modelling provides a parsimonious explanation for the ability of a single uORF to derepress translation during the integrated stress response
4. Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression
5. Roles for transcript leaders in translation and mRNA decay revealed by transcript leader sequencing
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