Unravelling the interplay between hyperkalaemia, renin–angiotensin–aldosterone inhibitor use and clinical outcomes. Data from 9222 chronic heart failure patients of the ESC‐HFA‐EORP Heart Failure Long‐Term Registry

Author:

Rossignol Patrick1,Lainscak Mitja2,Crespo‐Leiro Maria G.3,Laroche Cécile4,Piepoli Massimo F.5,Filippatos Gerasimos6,Rosano Giuseppe M.C.7,Savarese Gianluigi8,Anker Stefan D.9,Seferovic Petar M.10,Ruschitzka Frank11,Coats Andrew J.S.7,Mebazaa Alexandre12,McDonagh Theresa13,Sahuquillo Ana14,Penco Maria15,Maggioni Aldo P.416,Lund Lars H.17,Christopher Peter Gale GB,Branko Beleslin RS,Andrzej Budaj PL,Ovidiu Chioncel RO,Nikolaos Dagres DE,Nicolas Danchin FR,David Erlinge SE,Jonathan Emberson GB,Michael Glikson IL,Alastair Gray GB,Meral Kayikcioglu TR,Aldo Maggioni IT,Klaudia Vivien Nagy HU,Aleksandr Nedoshivin RU,Anna‐Sonia Petronio IT,Jolien Roos‐Hesselink NL,Lars Wallentin SE,Uwe Zeymer DE,Crespo‐Leiro M.,Anker S.,Mebazaa A.,Coats A.,Filippatos G.,Ferrari R.,Maggioni A.P.,Piepoli M.F.,Goda A.,Diez M.,Fernandez A.,Fruhwald F.,Fazlibegovic E.,Gatzov P.,Kurlianskaya A.,Hullin R.,Christodoulides T.,Hradec J.,Nielsen O. Wendelboe,Nedjar R.,Uuetoa T.,Hassanein M.,Jimenez J. F. Delgado,Harjola V.P.,Logeart D.,Chumburidze V.,Tousoulis D.,Milicic D.,Merkely B.,O'Donoghue E.,Amir O.,Shotan A.,Shafie D.,Metra M.,Matsumori A.,Mirrakhimov E.,Kavoliuniene A.,Erglis A.,Vataman E.,Otljanska M.,Kostovska E. Srbinovska,DeMarco D. Cassar,Drozdz J.,Fonseca C.,Chioncel O.,Dekleva M.,Shkolnik E.,Dahlstrom U.,Lainscak M.,Goncalvesova E.,Temizhan A.,Estrago V.,Bajraktari G.,Auer J.,Ablasser K.,Fruhwald F.,Dolze T.,Brandner K.,Gstrein S.,Poelzl G.,Moertl D.,Reiter S.,Podczeck‐Schweighofer A.,Muslibegovic A.,Vasilj M.,Fazlibegovic E.,Cesko M.,Zelenika D.,Palic B.,Pravdic D.,Cuk D.,Vitlianova K.,Katova T.,Velikov T.,Kurteva T.,Gatzov P.,Kamenova D.,Antova M.,Sirakova V.,Krejci J.,Mikolaskova M.,Spinar J.,Krupicka J.,Malek F.,Hegarova M.,Lazarova M.,Monhart Z.,Hassanein M.,Sobhy M.,El Messiry F.,El Shazly A.H.,Elrakshy Y.,Youssef A.,Moneim A.A.,Noamany M.,Reda A.,Dayem T.K. Abdel,Farag N.,Halawa S. Ibrahim,Hamid M. Abdel,Said K.,Saleh A.,Ebeid H.,Hanna R.,Aziz R.,Louis O.,Enen M.A.,Ibrahim B.S.,Nasr G.,Elbahry A.,Sobhy H.,Ashmawy M.,Gouda M.,Aboleineen W.,Bernard Y.,Luporsi P.,Meneveau N.,Pillot M.,Morel M.,Seronde M‐F.,Schiele F.,Briand F.,Delahaye F.,Damy T.,Eicher J‐C.,Groote P.,Fertin M.,Lamblin N.,Isnard R.,Lefol C.,Thevenin S.,Hagege A.,Jondeau G.,Logeart D.,Le Marcis V.,Ly J‐F.,Coisne D.,Lequeux B.,Le Moal V.,Mascle S.,Lotton P.,Behar N.,Donal E.,Thebault C.,Ridard C.,Reynaud A.,Basquin A.,Bauer F.,Codjia R.,Galinier M.,Tourikis P.,Stavroula M.,Tousoulis D.,Stefanadis C.,Chrysohoou C.,Kotrogiannis I.,Matzaraki V.,Dimitroula T.,Karavidas A.,Tsitsinakis G.,Kapelios C.,Nanas J.,Kampouri H.,Nana E.,Kaldara E.,Eugenidou A.,Vardas P.,Saloustros I.,Patrianakos A.,Tsaknakis T.,Evangelou S.,Nikoloulis N.,Tziourganou H.,Tsaroucha A.,Papadopoulou A.,Douras A.,Polgar L.,Merkely B.,Kosztin A.,Nyolczas N.,Nagy A. Csaba,Halmosi R.,Elber J.,Alony I.,Shotan A.,Fuhrmann A. Vazan,Amir O.,Romano S.,Marcon S.,Penco M.,Di Mauro M.,Lemme E.,Carubelli V.,Rovetta R.,Metra M.,Bulgari M.,Quinzani F.,Lombardi C.,Bosi S.,Schiavina G.,Squeri A.,Barbieri A.,Di Tano G.,Pirelli S.,Ferrari R.,Fucili A.,Passero T.,Musio S.,Di Biase M.,Correale M.,Salvemini G.,Brognoli S.,Zanelli E.,Giordano A.,Agostoni P.,Italiano G.,Salvioni E.,Copelli S.,Modena M.G.,Reggianini L.,Valenti C.,Olaru A.,Bandino S.,Deidda M.,Mercuro G.,Dessalvi C. Cadeddu,Marino P.N.,Di Ruocco M.V.,Sartori C.,Piccinino C.,Parrinello G.,Licata G.,Torres D.,Giambanco S.,Busalacchi S.,Arrotti S.,Novo S.,Inciardi R.M.,Pieri P.,Chirco P.R.,Galifi M. Ausilia,Teresi G.,Buccheri D.,Minacapelli A.,Veniani M.,Frisinghelli A.,Priori S.G.,Cattaneo S.,Opasich C.,Gualco A.,Pagliaro M.,Mancone M.,Fedele F.,Cinque A.,Vellini M.,Scarfo I.,Romeo F.,Ferraiuolo F.,Sergi D.,Anselmi M.,Melandri F.,Leci E.,Iori E.,Bovolo V.,Pidello S.,Frea S.,Bergerone S.,Botta M.,Canavosio F.G.,Gaita F.,Merlo M.,Cinquetti M.,Sinagra G.,Ramani F.,Fabris E.,Stolfo D.,Artico J.,Miani D.,Fresco C.,Daneluzzi C.,Proclemer A.,Cicoira M.,Zanolla L.,Marchese G.,Torelli F.,Vassanelli C.,Voronina N.,Erglis A.,Tamakauskas V.,Smalinskas V.,Karaliute R.,Petraskiene I.,Kazakauskaite E.,Rumbinaite E.,Kavoliuniene A.,Vysniauskas V.,Brazyte‐Ramanauskiene R.,Petraskiene D.,Stankala S.,Switala P.,Juszczyk Z.,Sinkiewicz W.,Gilewski W.,Pietrzak J.,Orzel T.,Kasztelowicz P.,Kardaszewicz P.,Lazorko‐Piega M.,Gabryel J.,Mosakowska K.,Bellwon J.,Rynkiewicz A.,Raczak G.,Lewicka E.,Dabrowska‐Kugacka A.,Bartkowiak R.,Sosnowska‐Pasiarska B.,Wozakowska‐Kaplon B.,Krzeminski A.,Zabojszcz M.,Mirek‐Bryniarska E.,Grzegorzko A.,Bury K.,Nessler J.,Zalewski J.,Furman A.,Broncel M.,Poliwczak A.,Bala A.,Zycinski P.,Rudzinska M.,Jankowski L.,Kasprzak J.D.,Michalak L.,Soska K. Wojtczak,Drozdz J.,Huziuk I.,Retwinski A.,Flis P.,Weglarz J.,Bodys A.,Grajek S.,Kaluzna‐Oleksy M.,Straburzynska‐Migaj E.,Dankowski R.,Szymanowska K.,Grabia J.,Szyszka A.,Nowicka A.,Samcik M.,Wolniewicz L.,Baczynska K.,Komorowska K.,Poprawa I.,Komorowska E.,Sajnaga D.,Zolbach A.,Dudzik‐Plocica A.,Abdulkarim A‐F.,Lauko‐Rachocka A.,Kaminski L.,Kostka A.,Cichy A.,Ruszkowski P.,Splawski M.,Fitas G.,Szymczyk A.,Serwicka A.,Fiega A.,Zysko D.,Krysiak W.,Szabowski S.,Skorek E.,Pruszczyk P.,Bienias P.,Ciurzynski M.,Welnicki M.,Mamcarz A.,Folga A.,Zielinski T.,Rywik T.,Leszek P.,Sobieszczanska‐Malek M.,Piotrowska M.,Kozar‐Kaminska K.,Komuda K.,Wisniewska J.,Tarnowska A.,Balsam P.,Marchel M.,Opolski G.,Kaplon‐Cieslicka A.,Gil R.J.,Mozenska O.,Byczkowska K.,Gil K.,Pawlak A.,Michalek A.,Krzesinski P.,Piotrowicz K.,Uzieblo‐Zyczkowska B.,Stanczyk A.,Skrobowski A.,Ponikowski P.,Jankowska E.,Rozentryt P.,Polonski L.,Gadula‐Gacek E.,Nowalany‐Kozielska E.,Kuczaj A.,Kalarus Z.,Szulik M.,Przybylska K.,Klys J.,Prokop‐Lewicka G.,Kleinrok A.,Aguiar C. Tavares,Ventosa A.,Pereira S.,Faria R.,Chin J.,De Jesus I.,Santos R.,Silva P.,Moreno N.,Queirós C.,Lourenço C.,Pereira A.,Castro A.,Andrade A.,Guimaraes T. Oliveira,Martins S.,Placido R.,Lima G.,Brito D.,Francisco A.R.,Cardiga R.,Proenca M.,Araujo I.,Marques F.,Fonseca C.,Moura B.,Leite S.,Campelo M.,Silva‐Cardoso J.,Rodrigues J.,Rangel I.,Martins E.,Correia A. Sofia,Peres M.,Marta L.,Silva G. Ferreira,Severino D.,Durao D.,Leao S.,Magalhaes P.,Moreira I.,Cordeiro A. Filipa,Ferreira C.,Araujo C.,Ferreira A.,Baptista A.,Radoi M.,Bicescu G.,Vinereanu D.,Sinescu C‐J.,Macarie C.,Popescu R.,Daha I.,Dan G‐A.,Stanescu C.,Dan A.,Craiu E.,Nechita E.,Aursulesei V.,Christodorescu R.,Otasevic P.,Seferovic P.M.,Simeunovic D.,Ristic A.D.,Celic V.,Pavlovic‐Kleut M.,Lazic J. Suzic,Stojcevski B.,Pencic B.,Stevanovic A.,Andric A.,Simić Dragan,Ašanin Milika,Iric‐Cupic V.,Jovic M.,Davidovic G.,Milanov S.,Mitic V.,Atanaskovic V.,Antic S.,Pavlovic M.,Stanojevic D.,Stoickov V.,Ilic S.,Ilic M. Deljanin,Petrovic D.,Stojsic S.,Kecojevic S.,Dodic S.,Adic N. Cemerlic,Cankovic M.,Stojiljkovic J.,Mihajlovic B.,Radin A.,Radovanovic S.,Krotin M.,Klabnik A.,Goncalvesova E.,Pernicky M.,Murin J.,Kovar F.,Kmec J.,Semjanova H.,Strasek M.,Iskra M. Savnik,Ravnikar T.,Suligoj N. Cernic,Komel J.,Fras Z.,Jug B.,Glavic T.,Losic R.,Bombek M.,Krajnc I.,Krunic B.,Horvat S.,Kovac D.,Rajtman D.,Cencic V.,Letonja M.,Winkler R.,Valentincic M.,Melihen‐Bartolic C.,Bartolic A.,Vrckovnik M. Pusnik,Kladnik M.,Pusnik C. Slemenik,Marolt A.,Klen J.,Drnovsek B.,Leskovar B.,Anguita M.J. Fernandez,Page J.C. Gallego,Martinez F.M. Salmeron,Andres J.,Bayes‐Genis A.,Mirabet S.,Mendez A.,Garcia‐Cosio L.,Roig E.,Leon V.,Gonzalez‐Costello J.,Muntane G.,Garay A.,Alcade‐Martinez V.,Fernandez S. Lopez,Rivera‐Lopez R.,Puga‐Martinez M.,Fernandez‐Alvarez M.,Serrano‐Martinez J.L.,Crespo‐Leiro M.,Grille‐Cancela Z.,Marzoa‐Rivas R.,Blanco‐Canosa P.,Paniagua‐Martin M.J.,Barge‐Caballero E.,Cerdena I. Laynez,Baldomero I. Famara Hernandez,Padron A. Lara,Rosillo S. Ofelia,Gonzalez‐Gallarza R. Dalmau,Montanes O. Salvador,Manjavacas A.M. Iniesta,Conde A. Castro,Araujo A.,Soria T.,Garcia‐Pavia P.,Gomez‐Bueno M.,Cobo‐Marcos M.,Alonso‐Pulpon L.,Cubero J. Segovia,Sayago I.,Gonzalez‐Segovia A.,Briceno A.,Subias P. Escribano,Hernandez M. Vicente,Cano M.J. Ruiz,Sanchez M.A. Gomez,Jimenez J.F. Delgado,Garrido‐Lestache E. Barrios,Pinilla J.M. Garcia,Villa B. Garcia,Sahuquillo A.,Marques R. Bravo,Calvo F. Torres,Perez‐Martinez M.T.,Gracia‐Rodenas M.R.,Garrido‐Bravo I. P.,Pastor‐Perez F.,Pascual‐Figal D.A.,Molina B. Diaz,Orus J.,Gonzalo F. Epelde,Bertomeu V.,Valero R.,Martinez‐Abellan R.,Quiles J.,Rodrigez‐Ortega J.A.,Mateo I.,ElAmrani A.,Fernandez‐Vivancos C.,Valero D. Bierge,Almenar‐Bonet L.,Sanchez‐Lazaro I.J.,Marques‐Sule E.,Facila‐Rubio L.,Perez‐Silvestre J.,Garcia‐Gonzalez P.,Ridocci‐Soriano F.,Garcia‐Escriva D.,Pellicer‐Cabo A.,Fuente Galan L.,Diaz J. Lopez,Platero A. Recio,Arias J.C.,Blasco‐Peiro T.,Julve M. Sanz,Sanchez‐Insa E.,Aured‐Guallar C.,Portoles‐Ocampo A.,Melin M.,Hägglund E.,Stenberg A.,Lindahl I‐M.,Asserlund B.,Olsson L.,Dahlström U.,Afzelius M.,Karlström P.,Tengvall L.,Olsson B.,Kalayci S.,Temizhan A.,Cavusoglu Y.,Gencer E.,Yilmaz M.B.,Gunes H.,

Affiliation:

1. Université de Lorraine, Centre d'Investigation Clinique Plurithématique 1433‐INSERM‐CHRU de Nancy Inserm U1116 & FCRIN INI‐CRCT (Cardiovascular and Renal Clinical Trialists) Nancy France

2. Division of Cardiology, General Hospital Murska Sobota, Murska Sobota and Faculty of Medicine University of Ljubljana Ljubljana Slovenia

3. Unidad de Insuficiencia Cardiaca y Trasplante Cardiaco, Complexo Hospitalario Universitario A Coruna (CHUAC) INIBIC, UDC, CIBERCV La Coruna Spain

4. EURObservational Research Programme European Society of Cardiology Sophia‐Antipolis France

5. Heart Failure Unit, Cardiac Department G. da Saliceto Hospital AUSL Piacenza Italy

6. School of Medicine, University of Cyprus & Heart Failure Unit, Department of Cardiology University Hospital Attikon, National and Kapodistrian University of Athens Athens Greece

7. IRCCS San Raffaele Pisana Rome Italy

8. Division of Cardiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden; Heart and Vascular Theme Karolinska University Hospital Stockholm Sweden

9. Department of Cardiology (CVK), and Berlin Institute of Health Center for Regenerative Therapies (BCRT); German Centre for Cardiovascular Research (DZHK) partner site Berlin Charité Universitätsmedizin Berlin Germany

10. University of Belgrade Faculty of Medicine Belgrade Serbia

11. University Hospital, Clinic of Cardiology Zurich Switzerland

12. UMR 942 Inserm MASCOT, Université de Paris; APHP Saint Louis Lariboisière University Hospitals Department of Anesthesia‐Burn‐Critical Care and FCRIN INI‐CRCT (Cardiovascular and Renal Clinical Trialists), Paris France

13. King's College Hospital London UK

14. Hospital de Manacor Balearic Island Spain

15. Cardiology University of L'Aquila L'Aquila Italy

16. ANMCO Research Center Florence Italy

17. Unit of Cardiology, Department of Medicine, Karolinska Institutet, and Heart and Vascular Theme Karolinska University Hospital Stockholm Sweden

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine

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