Functional desensitization of theβ2adrenoceptor is not dependent on agonist efficacy
Author:
Affiliation:
1. Novartis Institutes for Biomedical Research; Wimblehurst Road Horsham West Sussex RH12 5AB United Kingdom
2. School of Life Sciences; Queen's Medical Centre; University of Nottingham; Nottingham NG7 2UH United Kingdom
Publisher
Wiley
Subject
General Pharmacology, Toxicology and Pharmaceutics,Neurology
Reference33 articles.
1. Subsensitivity to bronchoprotection against adenosine monophosphate challenge following regular once-daily formoterol;Aziz;Eur Respir J,1998
2. Rapid onset of tolerance to the bronchoprotective effect of salmeterol;Bhagat;Chest,1995
3. Signaling by internalized G-protein-coupled receptors;Calebiro;Trends Pharmacol Sci,2010
4. Characterization of isoprenaline- and salmeterol-stimulated interactions between beta 2-adrenoceptors and beta-arrestin 2 using beta-galactosidase complementation in C2C12 cells;Carter;J Pharmacol Exp Ther,2005
5. Long-term safety and efficacy of indacaterol, a long-acting β2-agonist, in subjects with COPD: a randomized, placebo-controlled study;Chapman;Chest,2011
Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. ROS-mediated regulation of β2AR function: Does oxidation play a meaningful role towards β2-agonist tachyphylaxis in airway obstructive diseases?;Biochemical Pharmacology;2024-08
2. Key aspects of modern GPCR drug discovery;SLAS Discovery;2024-01
3. Beta-blockers reduce severe exacerbation in patients with mild chronic obstructive pulmonary disease with atrial fibrillation: a population-based cohort study;BMJ Open Respiratory Research;2023-11
4. “As-Needed” Inhaled Corticosteroids for Patients With Asthma;The Journal of Allergy and Clinical Immunology: In Practice;2023-03
5. Angiotensin II Type 1 Receptor Tachyphylaxis Is Defined by Agonist Residence Time;Hypertension;2022-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3