Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform-Reference-Cited by-同舟云学术

Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform

Published:2019-01-07 Issue:6 Volume:58 Page:341-356
ISSN:1045-2257
Container-title:Genes, Chromosomes and Cancer
language:en
Short-container-title:Genes Chromosomes Cancer

Author:

Bikkul Mehmet U.¹,Faragher Richard G. A.²,Worthington Gemma¹,Meinke Peter³⁴,Kerr Alastair R. W.⁴,Sammy Aakila¹,Riyahi Kumars¹,Horton Daniel¹,Schirmer Eric C.⁴,Hubank Michael⁵,Kill Ian R.¹,Anderson Rhona M.¹,Slijepcevic Predrag¹,Makarov Evgeny¹,Bridger Joanna M.¹^ORCID

Affiliation:

1. Genome Engineering and Maintenance NetworkInstitute for Environment, Health and Societies, Brunel University London Uxbridge England

2. Pharmacy and Biomolecular SciencesUniversity of Brighton Brighton England

3. Friedrich‐Baur‐InstitutKlinikum der Universität München München Germany

4. The Wellcome Trust Centre for Cell BiologyInstitute of Cell Biology, and Centre for Translational and Chemical Biology, University of Edinburgh Edinburgh England

5. Centre for Molecular PathologyThe Royal Marsden Hospital London England

Funder

Brunel Progeria Research Fund

Publisher

Wiley

Subject

Cancer Research,Genetics

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/gcc.22711

Reference121 articles.

1. Four faces of cellular senescence

2. Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors