In Vitro Model for a Drug Assessment of Cytochrome P450 Family 3 Subfamily A Member 4 Substrates Using Human Induced Pluripotent Stem Cells and Genome Editing Technology-Reference-Cited by-同舟云学术

In Vitro Model for a Drug Assessment of Cytochrome P450 Family 3 Subfamily A Member 4 Substrates Using Human Induced Pluripotent Stem Cells and Genome Editing Technology

Published:2021-05-05 Issue:8 Volume:5 Page:1385-1399
ISSN:2471-254X
Container-title:Hepatology Communications
language:en
Short-container-title:Hepatol Commun

Author:

Deguchi Sayaka¹,Shintani Tomohiro¹,Harada Kazuo²,Okamoto Toru³,Takemura Akinori⁴,Hirata Kazumasa²,Ito Kousei⁴,Takayama Kazuo¹⁵,Mizuguchi Hiroyuki¹⁶⁷⁸

Affiliation:

1. Laboratory of Biochemistry and Molecular Biology Graduate School of Pharmaceutical Sciences Osaka University Osaka Japan

2. Laboratory of Applied Environmental Biology Graduate School of Pharmaceutical Sciences Osaka University Osaka Japan

3. Institute for Advanced Co‐creation Studies, Research Institute for Microbial Diseases Osaka University Osaka Japan

4. Laboratory of Biopharmaceutics Graduate School of Pharmaceutical Sciences Chiba University Chiba Japan

5. Center for Induced Pluripotent Stem Cell Research and Application Kyoto University Kyoto Japan

6. Laboratory of Hepatocyte Regulation National Institutes of Biomedical Innovation, Health and Nutrition Osaka Japan

7. Global Center for Medical Engineering and Informatics Osaka University Osaka Japan

8. Integrated Frontier Research for Medical Science Division of the Institute for Open and Transdisciplinary Research Initiatives Osaka University Osaka Japan

Funder

Uehara Memorial Foundation

Mochida Memorial Foundation for Medical and Pharmaceutical Research

Japan Agency for Medical Research and Development

Publisher

Wiley

Subject

Hepatology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/hep4.1729

Reference35 articles.

1. Cytochromes P450 and metabolism of xenobiotics