An unusual case of interstitial lung disease: Revisiting peribronchiolar metaplasia interstitial lung disease (PBM‐ILD)

Author:

Jung Flora1,Shapera Shane1,Cabanero Michael2,McInnis Micheal3,Fisher Jolene1ORCID

Affiliation:

1. Department of Medicine University of Toronto Toronto Ontario Canada

2. University Health Network Ontario Cancer Institute/Prince Margaret Cancer Center Toronto Ontario Canada

3. Department of Medical Imaging University Health Network, University of Toronto Toronto Ontario Canada

Abstract

AbstractPeribronchiolar metaplasia (PBM) is a histological finding of uncertain significance commonly seen in interstitial lung disease (ILD). PBM is thought to be secondary to small airway injury from insults such as tobacco smoke and other environmental exposures. The term PBM‐ILD has been proposed for patients with ILD where PBM is the major histologic finding, however a lack of radiographic changes supportive of ILD in previously reported cases has limited recognition of the diagnosis. We present a rare case of welding‐associated ILD with clinical, radiographic, and histologic evidence consistent with the proposed definition of PBM‐ILD. We outline an approach to its consideration as a diagnosis based on our experience through multidisciplinary discussion.

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

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