Cell Mass Increase Associated with Formation of Glucose-Controlling β-Cell Mass in Device-Encapsulated Implants of hiPS-Derived Pancreatic Endoderm
Author:
Affiliation:
1. Diabetes Research Center Brussels Free University-VUB, Brussels, Belgium
2. Beta Cell Therapy Consortium, Brussels, Belgium
3. University Hospital Brussels-UZB, Brussels, Belgium
4. Nestlé Research, Lausanne, Switzerland
Abstract
Funder
Flemish Government
Juvenile Diabetes Research Foundation International
European Commission
Vlaamse regering
Publisher
Oxford University Press (OUP)
Subject
Cell Biology,Developmental Biology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/sctm.19-0043
Reference23 articles.
1. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo;Kroon;Nat Biotechnol,2008
2. A scalable system for production of functional pancreatic progenitors from human embryonic stem cells;Schulz;PLoS One,2012
3. Insulin-producing endocrine cells differentiated in vitro from human embryonic stem cells function in macroencapsulation devices in vivo;Agulnick;Stem Cells Translational Medicine,2015
4. Composition and function of macroencapsulated human embryonic stem cell-derived implants: Comparison with clinical human islet cell grafts;Motté;Am J Physiol Endocrinol Metab,2014
5. Functional beta cell mass from device-encapsulated hESC-derived pancreatic endoderm achieving metabolic control;Robert;Stem Cell Rep,2018
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