The antirheumatic drug leflunomide inhibits osteoclastogenesis by interfering with receptor activator of NF-κB ligand-stimulated induction of nuclear factor of activated T cells c1-Reference-Cited by-同舟云学术

The antirheumatic drug leflunomide inhibits osteoclastogenesis by interfering with receptor activator of NF-κB ligand-stimulated induction of nuclear factor of activated T cells c1

Published:2004-03 Issue:3 Volume:50 Page:794-804
ISSN:0004-3591
Container-title:Arthritis & Rheumatism
language:en
Short-container-title:Arthritis & Rheumatism

Author:

Urushibara Makoto,Takayanagi Hiroshi,Koga Takako,Kim Sunhwa,Isobe Miho,Morishita Yasuyuki,Nakagawa Takumi,Löeffler Monika,Kodama Tatsuhiko,Kurosawa Hisashi,Taniguchi Tadatsugu

Funder

Ministry of Education, Culture, Sports, Science, and Technology of Japan

PRESTO, Japan Science and Technology Corporation (JST)

Center of Excellence (COE) Program for Frontier Research on Molecular Destruction and Reconstruction of Tooth and Bone

Japan Society for the Promotion of Science, Health Sciences Research Grants from the Ministry of Health, Labour and Welfare of Japan

Japan Orthopaedics and Traumatology Foundation

Publisher

Wiley

Subject

Pharmacology (medical),Immunology,Rheumatology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/art.20206/fullpdf

Reference42 articles.

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2. Anti-TNFα therapy of rheumatoid arthritis: what have we learned?;Feldmann;Annu Rev Immunol,2001

3. Cytokine pathways and joint inflammation in rheumatoid arthritis;Choy;N Engl J Med,2001

4. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand;Kong;Nature,1999

5. Involvement of receptor activator of nuclear factor κB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis;Takayanagi;Arthritis Rheum,2000

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