Pilot PET Study to Assess the Functional Interplay Between ABCB1 and ABCG2 at the Human Blood

Pilot PET Study to Assess the Functional Interplay Between ABCB1 and ABCG2 at the Human Blood–Brain Barrier

Published:2016-05-09 Issue:2 Volume:100 Page:131-141
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Bauer M¹,Römermann K²,Karch R³,Wulkersdorfer B¹,Stanek J¹⁴,Philippe C⁵,Maier‐Salamon A⁶,Haslacher H⁷,Jungbauer C⁸,Wadsak W⁵⁹,Jäger W⁶,Löscher W²,Hacker M⁵⁹,Zeitlinger M¹,Langer O¹⁴⁵⁹

Affiliation:

1. Department of Clinical PharmacologyMedical University of ViennaVienna Austria

2. Department of Pharmacology, Toxicology & PharmacyUniversity of Veterinary MedicineHannover Germany

3. Center for Medical Statistics, Informatics and Intelligent SystemsMedical University of ViennaVienna Austria

4. Health and Environment DepartmentAIT Austrian Institute of Technology GmbHSeibersdorf Austria

5. Department of Biomedical Imaging und Image‐guided Therapy, Division of Nuclear MedicineMedical University of ViennaVienna Austria

6. Department of Clinical Pharmacy and DiagnosticsUniversity of ViennaVienna Austria

7. Department of Laboratory MedicineMedical University of ViennaVienna Austria

8. Austrian Red Cross Blood Transfusion ServicesVienna Austria

9. Medical Imaging ClusterMedical University of ViennaVienna Austria

Funder

Austrian Science Fund (FWF)

European Community's Seventh Framework program

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.362

Reference46 articles.

1. Why Clinical Modulation of Efflux Transport at the Human Blood–Brain Barrier Is Unlikely: The ITC Evidence-Based Position

2. Breast Cancer Resistance Protein and P-Glycoprotein in Brain Cancer: Two Gatekeepers Team Up

3. Apical ABC Transporters and Cancer Chemotherapeutic Drug Disposition

4. Local Drug-Drug Interaction of Donepezil with Cilostazol at Breast Cancer Resistance Protein (ABCG2) Increases Drug Accumulation in Heart

5. Inhibiting drug efflux transporters improves efficacy of ALS therapeutics

Cited by 51 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Blood–brain barrier transporters: a translational consideration for CNS delivery of neurotherapeutics;Expert Opinion on Drug Delivery;2024-01-02

3. In vitro identification of decreased function phenotype ABCG2 variants;European Journal of Pharmaceutical Sciences;2023-09

4. Genetic polymorphisms are associated with individual susceptibility to dexmedetomidine;Frontiers in Genetics;2023-08-24

5. In vivo methods for imaging blood–brain barrier function and dysfunction;European Journal of Nuclear Medicine and Molecular Imaging;2022-11-28