Free light chain content in culture media reflects recombinant monoclonal antibody productivity and quality-Reference-Cited by-同舟云学术

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Free light chain content in culture media reflects recombinant monoclonal antibody productivity and quality

Published:2013-06-25 Issue:5 Volume:29 Page:1131-1139
ISSN:8756-7938
Container-title:Biotechnology Progress
language:en
Short-container-title:Biotechnol Progress

Author:

Bhoskar Prachi¹,Belongia Brett²,Smith Robert³,Yoon Seongkyu⁴,Carter Tyler¹,Xu Jin¹

Affiliation:

1. Dept. of Chemistry; University of Massachusetts Lowell; Lowell MA

2. Bioreactor Process Development; EMD Millipore; Bedford MA

3. Process Analytical Technologies; EMD Millipore; Bedford MA

4. Dept. of Chemical Engineering; University of Massachusetts Lowell; Lowell MA

Publisher

Wiley

Subject

Biotechnology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/btpr.1767/fullpdf

Reference40 articles.

1. Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals;Butler;Appl Microbiol Biotechnol,2005

2. MAbs: a business perspective;Scolnik;MAbs,2009

3. Recombinant protein expression for therapeutic applications;Andersen;Curr Opin Biotech,2002

4. Industrial choices for protein production by large-scale cell culture;Chu;Curr Opin Biotechnol,2001

5. Current therapeutic antibody production and process optimization;Li;BioProcess J,2006

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4. An effective strategy for the humanization of antibody fragments under an accelerated timeline;International Journal of Biological Macromolecules;2022-09

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