Chimeric antigen receptor-engineered cytokine-induced killer cells overcome treatment resistance of pre-B-cell acute lymphoblastic leukemia and enhance survival

Author:

Oelsner Sarah12,Wagner Juliane23,Friede Miriam E.1,Pfirrmann Verena2,Genßler Sabrina1,Rettinger Eva2,Buchholz Christian J.45,Pfeifer Heike6,Schubert Ralf7,Ottmann Oliver G.8,Ullrich Evelyn23,Bader Peter2,Wels Winfried S.19

Affiliation:

1. Georg-Speyer-Haus; Institute for Tumor Biology and Experimental Therapy; Frankfurt Germany

2. Division for Stem Cell Transplantation and Immunology; Hospital for Children and Adolescents, Goethe University; Frankfurt Germany

3. LOEWE Center for Cell and Gene Therapy; Goethe University; Frankfurt Germany

4. Molecular Biotechnology and Gene Therapy; Paul-Ehrlich-Institut; Langen Germany

5. German Cancer Consortium (DKTK); Heidelberg Germany

6. Department of Medicine, Hematology and Oncology; Goethe University; Frankfurt Germany

7. Division for Allergology, Pneumology and Cystic Fibrosis; Hospital for Children and Adolescents, Goethe University; Frankfurt Germany

8. Department of Haematology, Division of Cancer and Genetics; Cardiff University School of Medicine; Cardiff United Kingdom

9. German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz; Germany

Funder

Deutsche Forschungsgemeinschaft

LOEWE Center for Cell and Gene Therapy Frankfurt (CGT)

Georg-Speyer-Haus, Stiftung Polytechnische Gesellschaft, Frankfurt am Main, German Federal Ministry of Health and the Ministry of Higher Education, Research and the Arts of the State of Hessen (HMWK)

Publisher

Wiley

Subject

Cancer Research,Oncology

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