Superior anticancer activity is demonstrated by total extract of Curcuma longa L. as opposed to individual curcuminoids separated by centrifugal partition chromatography

Author:

Kukula-Koch Wirginia1ORCID,Grabarska Aneta2,Łuszczki Jarogniew3,Czernicka Lidia4,Nowosadzka Ewa2,Gumbarewicz Ewelina2,Jarząb Agata2,Audo Gregoire5,Upadhyay Shakti6,Głowniak Kazimierz17,Stepulak Andrzej2

Affiliation:

1. Department of Pharmacognosy with Medicinal Plant Unit; Medical University of Lublin; 1 Chodźki 20-093 Lublin Poland

2. Department of Biochemistry and Molecular Biology; Medical University of Lublin; 1 Chodźki 20-093 Lublin Poland

3. Department of Pathophysiology; Medical University of Lublin; 8 Jaczewskiego 20-090 Lublin Poland

4. Department of Food and Nutrition; Medical University of Lublin; 4a Chodźki. 20-093 Lublin Poland

5. Armen Instrument Application Laboratory; ZI Kermelin 56890 Saint Avé France

6. Immunocon Biotech Sp. z o. o.; 39A Zana 20-601 Lublin Poland

7. Department of Cosmetology; University of Information Technology and Management; 2 Sucharskiego 35-225 Rzeszów Poland

Funder

National Science Center, Warsaw, Poland

Medical University of Lublin, Poland

Publisher

Wiley

Subject

Pharmacology

Reference34 articles.

1. Curcuma longa and curcumin;Akram;Romanian Journal of Biochemistry-Plant Biology,2010

2. Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives-A review;Amalraja;African Journal of Traditional, Complementary, and Alternative Medicines,2016

3. Curcumin inhibits hypoxia-induced angiogenesis via down-regulation of HIF-1;Bae;Oncology Reports,2006

4. Curcumin derivatives: Molecular basis of their anti-cancer activity;Basile;Biochemical Pharmacology,2009

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