Characterization and implications of host‐cell protein aggregates in biopharmaceutical processing-Reference-Cited by-同舟云学术

Characterization and implications of host‐cell protein aggregates in biopharmaceutical processing

Published:2023-01-12 Issue:4 Volume:120 Page:1068-1080
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotech & Bioengineering

Author:

Oh Young Hoon¹,Becker Matthew L.¹,Mendola Kerri M.¹,Choe Leila H.¹,Min Lie¹,Lee Kelvin H.¹^ORCID,Yigzaw Yinges²,Seay Alexander²,Bill Jerome²,Li Xuanwen³,Roush David J.⁴,Cramer Steven M.⁵^ORCID,Menegatti Stefano⁶,Lenhoff Abraham M.¹^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering University of Delaware Newark Delaware USA

2. Purification Process Development, Genentech, Inc. South San Francisco California USA

3. Analytical Research and Development, Merck & Co., Inc. Kenilworth New Jersey USA

4. Process Research and Development, Merck & Co., Inc. Rahway New Jersey USA

5. Department of Chemical and Biological Engineering Rensselaer Polytechnic Institute Troy New York USA

6. Department of Chemical and Biomolecular Engineering North Carolina State University Raleigh North Carolina USA

Funder

National Institute for Innovation in Manufacturing Biopharmaceuticals

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.28325

Reference47 articles.

1. A novel approach to monitor clearance of host cell proteins associated with monoclonal antibodies

2. Protein quality control and elimination of protein waste: The role of the ubiquitin–proteasome system

3. Quantitative definition and monitoring of the host cell protein proteome using iTRAQ - a study of an industrial mAb producing CHO-S cell line

4. MSstats: an R package for statistical analysis of quantitative mass spectrometry-based proteomic experiments

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