Activator protein 1 transcription factor fos-related antigen 1 (fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism

Author:

Hasenfuss Sebastian C.12,Bakiri Latifa1,Thomsen Martin K.1,Hamacher Rainer1,Wagner Erwin F.1

Affiliation:

1. Genes, Development and Disease Group, F-BBVA Cancer Cell Biology Programme; National Cancer Research Centre (CNIO); Madrid Spain

2. University of Freiburg; Faculty of Biology; Freiburg Germany

Publisher

Wiley

Subject

Hepatology

Reference49 articles.

1. c-jun is essential for normal mouse development and hepatogenesis;Hilberg;Nature,1993

2. Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver;Behrens;EMBO J,2002

3. Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53;Eferl;Cell,2003

4. Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase;Hasselblatt;Proc Natl Acad Sci U S A,2007

5. Targeted disruption of the murine junD gene results in multiple defects in male reproductive function;Thepot;Development,2000

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