Design of experiment assisted concurrent enantioseparation of bupropion and hydroxybupropion by high-performance thin-layer chromatography

Author:

Bhatt Nejal M.1,Chavada Vijay D.1,Sanyal Mallika2,Shrivastav Pranav S.1ORCID

Affiliation:

1. Chemistry Department, School of Sciences; Gujarat University; Ahmedabad Gujarat India

2. Chemistry Department; St. Xavier's Science College; Ahmedabad Gujarat India

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry

Reference19 articles.

1. Chiral drugs: an overview;Nguyen;Int J Biomed Sci,2006

2. The FDA perspective on the development of stereoisomers;De Camp;Chirality,1989

3. Review of bupropion for smoking cessation;Richmond;Drug Alcohol Rev,2003

4. Stereoselective analysis of bupropion and hydroxyl-bupropion in human plasma and urine by LC/MS/MS;Coles;J Chromatogr B,2007

5. Resolution of enantiomers of bupropion and its metabolites by liquid chromatography;Batra;Biomed Chromatogr,2015

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