Developing scalable cultivation systems of hepatic spheroids for drug metabolism via genomic and functional analyses-Reference-Cited by-同舟云学术

Developing scalable cultivation systems of hepatic spheroids for drug metabolism via genomic and functional analyses

Published:2019-03-04 Issue:6 Volume:116 Page:1496-1508
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnology and Bioengineering

Author:

Ahn Jiwon¹,Lee Ho‐Joon¹^ORCID,Oh Soo Jin²,Kim Wantae³,Mun Seon Ju¹⁴,Lee Jae‐Hye¹⁴,Jung Cho‐Rock⁴⁵,Cho Hyun‐Soo¹⁴,Kim Dae‐Soo⁴⁶,Son Myung Jin¹⁴,Chung Kyung‐Sook¹³⁴^ORCID

Affiliation:

1. Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)Daejeon Republic of Korea

2. New Drug Development Center, Asan Medical Center and Convergence Medicine, University of UlsanSeoul Republic of Korea

3. Biomedical Translational Research Center, KRIBBDaejeon Republic of Korea

4. Functional Genomics, Korea University of Science and Technology (UST)Daejeon Republic of Korea

5. Gene Therapy Unit, KRIBBDaejeon Republic of Korea

6. Genome Research Center, KRIBBDaejeon Republic of Korea

Funder

Ministry of Education, Science and Technology

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.26954

Reference31 articles.

1. EXPRESSION OF CYTOCHROMES P450, CONJUGATING ENZYMES AND NUCLEAR RECEPTORS IN HUMAN HEPATOMA HepaRG CELLS

2. Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

3. Transdifferentiation of hepatocyte-like cells from the human hepatoma HepaRG cell line through bipotent progenitor

4. Advances in multicellular spheroids formation

5. The role of Notch receptor expression in bile duct development and disease

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