Assessment of programmed death-ligand 1 expression and tumor-associated immune cells in pediatric cancer tissues

Author:

Majzner Robbie G.1ORCID,Simon Jason S.2,Grosso Joseph F.2,Martinez Daniel34,Pawel Bruce R.34,Santi Mariarita34,Merchant Melinda S.5,Geoerger Birgit6,Hezam Imene6,Marty Virginie7,Vielh Phillippe7,Daugaard Mads89,Sorensen Poul H.10,Mackall Crystal L.1,Maris John M.114

Affiliation:

1. Department of Pediatrics; Stanford University; Stanford California

2. Bristol-Myers Squibb; Princeton New Jersey

3. Department of Pathology and Laboratory Medicine; Children's Hospital of Philadelphia; Philadelphia Pennsylvania

4. Perelman School of Medicine; University of Pennsylvania; Philadelphia Pennsylvania

5. Pediatric Oncology Branch, National Cancer Institute; Bethesda Maryland

6. Department of Pediatric and Adolescent Medicine; Gustave Roussy Institute; Villejuif France

7. Department of Medical Biology and Pathology; Gustave Roussy Institute; Villejuif France

8. Vancouver Prostate Center; Vancouver British Columbia Canada

9. Department of Urologic Sciences; University of British Columbia; Vancouver British Columbia Canada

10. British Columbia Cancer Agency; Vancouver British Columbia Canada

11. Department of Pediatrics; University of Pennsylvania; Philadelphia Pennsylvania

Funder

Bristol-Myers Squibb

Stand Up To Cancer

St. Baldrick's Foundation

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference65 articles.

1. The journey from discoveries in fundamental immunology to cancer immunotherapy;Miller;Cancer Cell,2015

2. Bristol-Myers Squibb YERVOY [package insert] http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/125377s00 00lbl.pdf 2016

3. Merck KEYTRUDA http://www.accessdata.fda.gov/drugsatfda_docs/label/2014/125514lbl.pdf 2016

4. Bristol-Myers Squibb OPDIVO http://www.accessdata.fda.gov/drugsatfda_docs/label/2014/125554lbl.pdf 2016

5. MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer;Powles;Nature,2014

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