Geniposide downregulates the VEGF / SphK1 / S1P pathway and alleviates angiogenesis in rheumatoid arthritis in vivo and in vitro-Reference-Cited by-同舟云学术

Geniposide downregulates the VEGF / SphK1 / S1P pathway and alleviates angiogenesis in rheumatoid arthritis in vivo and in vitro

Published:2021-06-21 Issue:8 Volume:35 Page:4347-4362
ISSN:0951-418X
Container-title:Phytotherapy Research
language:en
Short-container-title:Phytotherapy Research

Author:

Wang Yan¹²³⁴^ORCID,Wu Hong¹²³^ORCID,Deng Ran¹²³⁴,Dai Xue‐jing¹²³⁴^ORCID,Bu Yan‐hong¹²³⁴^ORCID,Sun Ming‐hui¹²³⁴^ORCID,Zhang Heng¹²³⁴^ORCID,Wang Meng‐die¹²³⁴^ORCID,Wang Rong‐hui¹²³⁴^ORCID

Affiliation:

1. College of Pharmacy Anhui University of Chinese Medicine Hefei China

2. Key Laboratory of Xin'an Medicine Ministry of Education Hefei China

3. Anhui Province Key Laboratory of Research & Development of Chinese Medicine Science and Technology Department of Anhui Province Hefei China

4. Anhui Province Key Laboratory of Chinese Medicinal Formula Science and Technology Department of Anhui Province Hefei China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.7130

Reference57 articles.

1. Dual blockade of VEGFR1 and VEGFR2 by a novel peptide abrogates VEGF-driven angiogenesis, tumor growth, and metastasis through PI3K/AKT and MAPK/ERK1/2 pathway

2. 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative;Aletaha D.;Multicenter Study,2010

3. Angiogenesis and the persistence of inflammation in a rat model of proliferative synovitis

4. Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells;Bazzazi H.;Hojjat Bazzazi,Aleksander S Popel,2017

5. Evaluation of therapeutic targets in animal models of arthritis: How does it relate to rheumatoid arthritis?

Cited by 31 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Influence of SphK1 on Inflammatory Responses in Lipopolysaccharide-Challenged RAW 264.7 Cells;Cell Biochemistry and Biophysics;2024-06-22

2. The protective effect of natural medicines in rheumatoid arthritis via inhibit angiogenesis;Frontiers in Pharmacology;2024-05-31

3. CPD-002, a novel VEGFR2 inhibitor, relieves rheumatoid arthritis by reducing angiogenesis through the suppression of the VEGFR2/PI3K/AKT signaling pathway;International Immunopharmacology;2024-04

4. Advantages of Chinese herbal medicine in treating rheumatoid arthritis: a focus on its anti-inflammatory and anti-oxidative effects;Frontiers in Medicine;2024-03-07

5. Assessment of the Effects of Sphingosine Kinase 1/Sphingosine-1-Phosphate on Microangiogenesis at Rat Myofascial Trigger Points Using Contrast-Enhanced Ultrasonography;Journal of Pain Research;2024-02