Heterozygosity for the alpha-1-antitrypsin Z allele in cirrhosis is associated with more advanced disease

Author:

Schaefer Benedikt1,Mandorfer Mattias2,Viveiros André1,Finkenstedt Armin1,Ferenci Peter2,Schneeberger Stefan3,Tilg Herbert1,Zoller Heinz1

Affiliation:

1. Department of Medicine I, Gastroenterology, Hepatology and Endocrinology; Medical University of Innsbruck; Innsbruck Austria

2. Division of Gastroenterology and Hepatology, Department of Internal Medicine III; Medical University of Vienna; Vienna Austria

3. Department of Visceral, Transplant and Thoracic Surgery; Medical University of Innsbruck; Innsbruck Austria

Funder

Medical University of Innsbruck

Verein zur Foerderung der Wissenschaft in Gastroenterologie and Hepatologie

Publisher

Wiley

Subject

Transplantation,Hepatology,Surgery

Reference24 articles.

1. α1-antitrypsin deficiency;Greene;Nat Rev Dis Primers,2016

2. Is severe progressive liver disease caused by alpha-1-antitrypsin deficiency more common in children or adults?;Chu;Liver Transpl,2016

3. Baseline analysis of a young alpha-1-antitrypsin deficiency liver disease cohort reveals frequent portal hypertension;Teckman;J Pediatr Gastroenterol Nutr,2015

4. Diagnosis and management of patients with alpha1-antitrypsin (A1AT) deficiency;Nelson;Clin Gastroenterol Hepatol,2012

5. Alpha1-antitrypsin deficiency. 2: genetic aspects of alpha(1)-antitrypsin deficiency: phenotypes and genetic modifiers of emphysema risk;DeMeo;Thorax,2004

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