Semiphysiologically Based Pharmacokinetic Model of Leflunomide Disposition in Rheumatoid Arthritis Patients-Reference-Cited by-同舟云学术

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Semiphysiologically Based Pharmacokinetic Model of Leflunomide Disposition in Rheumatoid Arthritis Patients

Published:2015-06 Issue:6 Volume:4 Page:362-371
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Hopkins AM¹²,Wiese MD²,Proudman SM³⁴,O'Doherty CE²,Foster DJR¹,Upton RN¹

Affiliation:

1. University of South Australia, Australian Centre for Pharmacometrics, School of Pharmacy and Medical SciencesAdelaide South Australia Australia

2. University of South Australia, Sansom Institute for Health Research, School of Pharmacy and Medical SciencesAdelaide South Australia Australia

3. Royal Adelaide Hospital, Department of RheumatologyAdelaide South Australia Australia

4. Adelaide University, Discipline of MedicineAdelaide South Australia Australia

Publisher

Wiley

Subject

Pharmacology (medical),Modelling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.46

Reference43 articles.

1. Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development

2. Physiologically based pharmacokinetic modelling: a sound mechanistic basis is needed

3. Kinetic determinants of hepatic clearance: Plasma protein binding and hepatic uptake

4. Basic Concepts in Physiologically Based Pharmacokinetic Modeling in Drug Discovery and Development

5. Leflunomide Inhibition of BK Virus Replication in Renal Tubular Epithelial Cells

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2. Leflunomide Exposure and Teriflunomide Concentrations up to the Third Trimester of Pregnancy: A Case Report;Clinical Drug Investigation;2022-07-27

3. Frequency and impact of DHODH, ABCG2 and CYP2C19 SNPs on the therapeutic efficacy, tolerability and toxicity of leflunomide;Pharmacogenomics;2021-12

4. The Mitochondria-Independent Cytotoxic Effect of Leflunomide on RPMI-8226 Multiple Myeloma Cell Line;Molecules;2021-09-17

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