Using a novel NQO1 bioactivatable drug, beta-lapachone (ARQ761), to enhance chemotherapeutic effects by metabolic modulation in pancreatic cancer-Reference-Cited by-同舟云学术

Using a novel NQO1 bioactivatable drug, beta-lapachone (ARQ761), to enhance chemotherapeutic effects by metabolic modulation in pancreatic cancer

Published:2017-03-27 Issue:1 Volume:116 Page:83-88
ISSN:0022-4790
Container-title:Journal of Surgical Oncology
language:en
Short-container-title:J Surg Oncol

Author:

Beg Muhammad Shaalan¹²^ORCID,Huang Xiumei²³,Silvers Molly A.²,Gerber David E.¹²,Bolluyt Joyce²,Sarode Venetia²⁴,Fattah Farjana²,Deberardinis Ralph J.³⁵,Merritt Matthew E.⁶,Xie Xian-Jin²,Leff Richard⁷,Laheru Daniel⁸,Boothman David A.²³

Affiliation:

1. Division of Hematology and Oncology; Department of Internal Medicine; University of Texas Southwestern Medical Center; Dallas Texas

2. Harold Simmons Comprehensive Cancer Center; University of Texas Southwestern Medical Center; Dallas Texas

3. Departments of Pharmacology and Radiation Oncology; University of Texas Southwestern Medical Center; Dallas Texas

4. Department of Pathology; University of Texas Southwestern Medical Center; Dallas Texas

5. Children‘s Medical Center Research Institute; University of Texas Southwestern Medical Center; Dallas Texas

6. Department of Biochemistry and Molecular Biology; University of Florida; Gainesville Florida

7. Clinical Pharmacology & Experimental Therapeutics Center; Texas Tech University Health Sciences Center; School of Pharmacy; Dallas Texas

8. Sidney Kimmel Cancer Center; Johns Hopkins University; Baltimore Maryland

Funder

Arqule Pharmaceuticals

National Cancer Institute

Cancer Prevention and Research Institute of Texas

Pancreatic Cancer Action Network

PanCan Translational Research Grant

Publisher

Wiley

Subject

Oncology,General Medicine,Surgery

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jso.24624/fullpdf

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