Transcriptional profiling of the mouse hippocampus supports an NMDAR‐mediated neurotoxic mode of action for benzo[ a ]pyrene-Reference-Cited by-同舟云学术

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Transcriptional profiling of the mouse hippocampus supports an NMDAR‐mediated neurotoxic mode of action for benzo[ a ]pyrene

Published:2016-05-19 Issue:5 Volume:57 Page:350-363
ISSN:0893-6692
Container-title:Environmental and Molecular Mutagenesis
language:en
Short-container-title:Environ. Mol. Mutagen.

Author:

Chepelev Nikolai L.¹,Long Alexandra S.¹,Bowers Wayne J.¹,Gagné Rémi¹,Williams Andrew¹,Kuo Byron¹,Phillips David H.²,Arlt Volker M.²,White Paul A.¹,Yauk Carole L.¹

Affiliation:

1. Environmental Health Science and Research BureauEnvironmental and Radiation Health Sciences Directorate, HECSB, Health CanadaOttawa Ontario CanadaK1A 0K9

2. Analytical and Environmental Sciences DivisionMRC‐PHE Centre for Environment and Health, King's College LondonLondonSE1 9NH United Kingdom

Funder

Cancer Research UK

Wellcome Trust

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Genetics (clinical),Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/em.22020

Reference54 articles.

1. HTSeq--a Python framework to work with high-throughput sequencing data

2. Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene

3. Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice

4. Benzo[α]pyrene-Induced Anti-Depressive-like Behaviour in Adult Female Mice: Role of Monoaminergic Systems

5. Down-regulation of early ionotrophic glutamate receptor subunit developmental expression as a mechanism for observed plasticity deficits following gestational exposure to benzo(a)pyrene

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