Statistical evaluation of surrogate endpoints with examples from cancer clinical trials

Author:

Buyse Marc12,Molenberghs Geert23,Paoletti Xavier4,Oba Koji5,Alonso Ariel3,Van der Elst Wim2,Burzykowski Tomasz26

Affiliation:

1. International Drug Development Institute (IDDI); 185 Alewife Brook Parkway, Suite 410 Cambridge MA 02138 USA

2. Interuniversity Institute for Biostatistics and Statistical Bioinformatics (I-BioStat); Hasselt University; Martelarenlaan 42 3500 Hasselt Belgium

3. Interuniversity Institute for Biostatistics and Statistical Bioinformatics (I-BioStat); KU Leuven-University of Leuven; Kapucijnenvoer 35 3000 Leuven Belgium

4. Department of Biostatistics; INSERM U900, Institut Curie; 26 Rue d'Ulm 75005 Paris France

5. Department of Biostatistics; School of Public Health, Graduate School of Medicine, and Interfaculty Initiative in Information Studies, University of Tokyo; 7-3-1 Hongo Bunkyo-ku Tokyo 113-0033 Japan

6. International Drug Development Institute (IDDI); avenue provinciale 30 1340 Louvain-la-Neuve Belgium

Publisher

Wiley

Subject

Statistics, Probability and Uncertainty,General Medicine,Statistics and Probability

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