Metformin normalizes the structural changes in glycogen preceding prediabetes in mice overexpressing neuropeptide Y in noradrenergic neurons

Author:

Ailanen Liisa12,Bezborodkina Natalia N.3,Virtanen Laura1,Ruohonen Suvi T.1,Malova Anastasia V.3,Okovityi Sergey V.4,Chistyakova Elizaveta Y.4,Savontaus Eriika15ORCID

Affiliation:

1. Institute of Biomedicine; Research Center for Integrative Physiology and Pharmacology and Turku Center for Disease Modelling; University of Turku; Turku Finland

2. Drug Research Doctoral Program; University of Turku; Turku Finland

3. Laboratory of Cellular Pathology; Institute of Cytology of the Russian Academy of Sciences; St. Petersburg Russia

4. Department of Pharmacology and Clinical Pharmacology; Saint-Petersburg State Chemical Pharmaceutical Academy; St. Petersburg Russia

5. Unit of Clinical Pharmacology; Turku University Hospital; Turku Finland

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Reference54 articles.

1. The regulation of glucose metabolism: implications and considerations for the assessment of glucose homeostasis in rodents;Kowalski;Am J Physiol Endocrinol Metab,2014

2. Diurnal variation in skeletal muscle and liver glycogen in humans with normal health and Type 2 diabetes;Macauley;Clin Sci,2015

3. Hepatic glycogen metabolism in the db/db mouse;Roesler;Mol Cell Biochem,1990

4. Ultrastructural characteristics of rats liver in norm and in experimental diabetes mellitus on late terms of run;Sogujko;Med Pharm,2013

5. Monitoring of liver glycogen synthesis in diabetic patients using carbon-13 MR spectroscopy;Tomiyasu;Eur J Radiol,2010

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