Affiliation:
1. United States Anti‐doping Agency Colorado Springs Colorado USA
2. Sports Medicine Research Testing Laboratory Salt Lake City Utah USA
3. Bryam Hills, Armonk New York New York USA
4. Athletics Integrity Unit Monaco
Abstract
AbstractBlood collection is an important facet of anti‐doping testing, forming the basis of the Athlete Biological Passport (ABP). Traditional blood collection via venipuncture can be uncomfortable for athletes, especially those who are tested frequently or close to competition. Athletes may also have negative perceptions of venipuncture due to past experiences or the risks of adverse health events such as bruising, hematomas, syncope, and general discomfort that has the potential to affect performance. Advances in capillary whole blood collection technology now affords the ability to collect micro‐volumetric capillary whole blood from the upper arm (or other suitable vascular location such as the abdomen) that is “needle‐free” and virtually painless using devices such as the Tasso+. The present study extends previous work, by collecting microliter capillary whole blood samples via the Tasso+ EDTA device in an official anti‐doping setting prior to competition, as well as requiring temperature‐monitored cold chain shipping by air to the laboratory before analysis. Fifty‐eight matched capillary and venous blood samples were collected under official doping control conditions by certified Doping Control Officers. No impact of sample shipment by air under cool conditions was observed on sample integrity. Provided that no visible clots were identified prior to analysis, capillary and venous blood samples showed excellent laboratory agreement for all CBC parameters, with the exception of platelets. Micro capillary blood collection provides a valid alternative to venous blood collection for ABP purposes, with the advantage of providing a more athlete‐friendly experience, particularly close to competition.
Subject
Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry
Reference6 articles.
1. Tasso Inc.Tasso+ device instructions.2022. [9 September 2023]; Available from:https://www.tassoinc.com/tasso-plus
2. Feasibility of microvolumetric capillary whole blood collections for usage in Athlete Biological Passport analysis
3. WADA Athlete Biological Passport (ABP) operating guidelines.2023. [9 September 2023]; Available from:https://www.wada-ama.org/en/resources/world-anti-doping-program/athlete-biological-passport-abp-operating-guidelines
4. Influence of transport and time on blood variables commonly measured for the athlete biological passport
5. WADA Technical Document—TDBAR2021.2021. [9 September 2023]; Available from:https://www.wada-ama.org/en/resources/labdocuments/td2021bar
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献