Genome Engineering and Modification Toward Synthetic Biology for the Production of Antibiotics

Author:

Zou Xuan12,Wang Lianrong1,Li Zhiqiang1,Luo Jie2,Wang Yunfu2,Deng Zixin1,Du Shiming2,Chen Shi12

Affiliation:

1. Zhongnan Hospital, and Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences; Wuhan University; Wuhan Hubei 430071 China

2. Taihe Hospital; Hubei University of Medicine; Shiyan Hubei China

Funder

National Natural Science Foundation of China

973 programs of Ministry of Science and Technology

Young One Thousand Talent program of China

Hubei Province's Outstanding Medical Academic Leader Program

Publisher

Wiley

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Reference139 articles.

1. Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors. 1987;Burke;Biotechnology,1992

2. Functional expression of cloned yeast DNA in Escherichia coli;Ratzkin;Proc Natl Acad Sci USA,1977

3. Yeast artificial chromosomes: Tools for mapping and analysis of complex genomes;Schlessinger;Trends Genet,1990

4. Rapid modification of bacterial artificial chromosomes by ET-recombination;Muyrers;Nucl Acids Res,1999

5. The development and applications of the bacterial artificial chromosome cloning system;Shizuya;Keio J Med,2001

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