Evaluation of 6β-Hydroxycortisol and 6β-Hydroxycortisone as Biomarkers for Cytochrome P450 3A Activity: Insight into Their Predictive Value for Estimating Oral Immunosuppressant Metabolism-Reference-Cited by-同舟云学术

Evaluation of 6β-Hydroxycortisol and 6β-Hydroxycortisone as Biomarkers for Cytochrome P450 3A Activity: Insight into Their Predictive Value for Estimating Oral Immunosuppressant Metabolism

Published:2015-10 Issue:10 Volume:104 Page:3578-3586
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Luo Xi,Zheng Liyun,Cai Ningfang,Liu Qing,Yang Shuang,He Xiaoai,Cheng Zeneng

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference35 articles.

1. Cytochrome P450 3A: Genetic polymorphisms and inter-ethnic differences;Krishna;Methods Find Exp Clin Pharmacol,2005

2. Problems and perspectives of phenotyping for drug-metabolizing enzymes in man;Zaigler;Int J Clin Pharmacol Ther,2000

3. The genetic determinants of the CYP3A5 polymorphism;Hustert;Pharmacogenetics,2001

4. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression;Kuehl;Nat Genet,2001

5. Urinary 6β-hydroxycortisol: A validated test for evaluating drug induction or drug inhibition mediated through CYP3A in humans and in animals;Galteau;Eur J Clin Pharmacol,2003

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