Exploring the kinetic selectivity of drugs targeting the β <sub>1</sub> ‐adrenoceptor-Reference-Cited by-同舟云学术

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Exploring the kinetic selectivity of drugs targeting the β ₁ ‐adrenoceptor

Published:2022-06-28 Issue:4 Volume:10 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacology Res & Perspec

Author:

Sykes David A.¹²^ORCID,Jiménez‐Rosés Mireia¹²^ORCID,Reilly John³,Fairhurst Robin A.³,Charlton Steven J.¹²^ORCID,Veprintsev Dmitry B.¹²^ORCID

Affiliation:

1. Centre of Membrane Proteins and Receptors (COMPARE) University of Nottingham Midlands UK

2. Division of Physiology, Pharmacology & Neuroscience, School of Life Sciences University of Nottingham Nottingham UK

3. Novartis Institutes for BioMedical Research Basel Switzerland

Funder

Novartis Institutes for BioMedical Research

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.978

Reference58 articles.

1. Beta-blockade in asthma.

2. Cardiac‐specific beta‐blockers and asthma: An end to fear?

3. Pathway and mechanism of drug binding to G-protein-coupled receptors

4. Molecular Basis of Ligand Dissociation in β-Adrenergic Receptors

5. Comparison of Dynamics of Extracellular Accesses to the β1 and β2 Adrenoceptors Binding Sites Uncovers the Potential of Kinetic Basis of Antagonist Selectivity

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1. A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand binding assay;2024-07-18

2. High-throughput kinetics in drug discovery;SLAS Discovery;2024-07

3. β-blockers are not all the same: pharmacologic similarities and differences, potential combinations and clinical implications;Current Medical Research and Opinion;2024-04

4. Engineering of carbonyl reductase for asymmetric reduction of difficult-to-reduce ketone tetrahydrofuran-3-one;Molecular Catalysis;2023-09

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