Early termination of pivotal trials in Alzheimer's disease—Preserving optimal value for participants and science-Reference-Cited by-同舟云学术

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Early termination of pivotal trials in Alzheimer's disease—Preserving optimal value for participants and science

Published:2022-02-27 Issue:10 Volume:18 Page:1980-1987
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Gietl Anton F.¹²^ORCID,Frisoni Giovanni B.³

Affiliation:

1. Institute for Regenerative Medicine, Center for Prevention and Dementia Therapy University of Zurich Schlieren Switzerland

2. University Hospital for Geriatric Psychiatry Switzerland

3. Geneva University Hospital and University of Geneva Switzerland

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12605

Reference52 articles.

1. The Role of Futility Analyses in Alzheimer’s Disease Clinical Trials

2. FUTILITY ANALYSES IN ALZHEIMER’S DISEASE (AD) CLINICAL TRIALS: A RISKY BUSINESS

3. Reasons for Failed Trials of Disease-Modifying Treatments for Alzheimer Disease and Their Contribution in Recent Research

4. Lessons Learned from Alzheimer Disease: Clinical Trials with Negative Outcomes

5. Why do so many clinical trials of therapies for Alzheimer's disease fail?

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