Hydrophobicity predicts in vivo19F magnetic resonance detectability of fluorinated psychiatric drugs: simple test for likely success in clinical pharmacokinetic studies
Author:
Publisher
Wiley
Subject
Drug Discovery
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ddr.20254/fullpdf
Reference20 articles.
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3. Fluorinated psychopharmacological agents: noninvasive observation by fluorine-19 nuclear magnetic resonance;Bartels;Psychiatry Res,1986
4. 19F nuclear magnetic resonance spectroscopy of neuroleptics: the first in vivo pharmacokinetics of trifluoperazine in the rat brain and the first in vivo spectrum of fluphenazine in the human brain;Bartels;Biol Psychiatry,1991
5. Brain pharmacokinetics and tissue distribution in vivo of fluvoxamine and fluoxetine by fluorine magnetic resonance spectroscopy;Bolo;Neuropsychopharmacology,2000
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