DOCK4 stimulates MUC2 production through its effect on goblet cell differentiation

Author:

Qin Tingfeng1,Yang Jie1,Huang Dayin1,Zhang Zhijun1,Huang Yanling1,Chen Hui2,Xu Geyang1ORCID

Affiliation:

1. Department of Physiology, School of Medicine Jinan University  Tianhe Guangzhou Guangdong China

2. Cell‐Gene Therapy Translational Medicine Research Center The Third Affiliated Hospital of Sun Yat‐Sen University Guangzhou China

Funder

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference43 articles.

1. Calcium and pH-dependent packing and release of the gel-forming MUC2 mucin

2. Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis

3. Bennett P.(2016).A role for DOCK4 in intestinal barrier properties. (Master). Harvard Extension School.

4. New developments in goblet cell mucus secretion and function

5. SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production;Chen G.;Journal of Clinical Investigation,2009

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