One-Pot, Two-Step Hydroxylation of the Macrocyclic Diterpenoid β-Cembrenediol Catalyzed by P450 BM3 Mutants-Reference-Cited by-同舟云学术

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One-Pot, Two-Step Hydroxylation of the Macrocyclic Diterpenoid β-Cembrenediol Catalyzed by P450 BM3 Mutants

Published:2016-11-16 Issue:24 Volume:8 Page:3755-3761
ISSN:1867-3880
Container-title:ChemCatChem
language:en
Short-container-title:ChemCatChem

Author:

Le-Huu Priska¹,Petrović Dušan²,Strodel Birgit²³,Urlacher Vlada B.¹

Affiliation:

1. Institute of Biochemistry; Heinrich-Heine University Düsseldorf; Universitätsstrasse 1, Bldg. 26.42.U1 40225 Düsseldorf Germany

2. Institute of Complex Systems: Structural Biochemistry (ICS-6); Forschungszentrum Jülich GmbH; 52425 Jülich Germany

3. Institute of Theoretical and Computational Chemistry; Heinrich-Heine University Düsseldorf; Universitätsstrasse 1 40225 Düsseldorf Germany

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cctc.201600973/fullpdf

Reference79 articles.

1. Cytochromes P450 for Terpene Functionalisation and Metabolic Engineering

2. Research progress relating to the role of cytochrome P450 in the biosynthesis of terpenoids in medicinal plants

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1. Choose Your Own Adventure: A Comprehensive Database of Reactions Catalyzed by Cytochrome P450 BM3 Variants;ACS Catalysis;2024-03-29

2. Hydroxylases involved in terpenoid biosynthesis: a review;Bioresources and Bioprocessing;2023-07-13

3. Opportunities for Accelerating Drug Discovery and Development by Using Engineered Drug-Metabolizing Enzymes;Drug Metabolism and Disposition;2022-12-02

4. A Promiscuous Bacterial P450: The Unparalleled Diversity of BM3 in Pharmaceutical Metabolism;International Journal of Molecular Sciences;2021-10-21

5. Engineered Cytochromes P 450 for Biocatalysis;Protein Engineering;2021-08-06

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