Two‐step Screening for Identification of Drug‐metabolizing Bacterial Cytochromes P450 with Diversified Selectivity-Reference-Cited by-同舟云学术

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Two‐step Screening for Identification of Drug‐metabolizing Bacterial Cytochromes P450 with Diversified Selectivity

Published:2020-03-19 Issue:6 Volume:12 Page:1710-1719
ISSN:1867-3880
Container-title:ChemCatChem
language:en
Short-container-title:ChemCatChem

Author:

Hilberath Thomas¹,Windeln Leonie M.¹,Decembrino Davide¹,Le‐Huu Priska¹,Bilsing Florestan L.¹,Urlacher Vlada B.¹^ORCID

Affiliation:

1. Institute of BiochemistryHeinrich-Heine University Düsseldorf Universitätsstrasse 1 Düsseldorf 40225 Germany

Funder

Bundesministerium für Bildung und Forschung

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cctc.201901967

Reference67 articles.

1.

2. Factors affecting the uptake of new medicines: a systematic literature review

3. Drug Discovery: A Historical Perspective

4.

5. Preclinical Pharmacokinetics: An Approach Towards Safer and Efficacious Drugs

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1. The thin line between monooxygenases and peroxygenases. P450s, UPOs, MMOs, and LPMOs: A brick to bridge fields of expertise;Biotechnology Advances;2024-05

2. Microbial P450 repertoire (P450ome) and its application feasibility in pharmaceutical industry, chemical industry, and environmental protection;Biotechnology and Bioengineering;2023-09-28

3. Bacterial cytochrome P450 enzymes: Semi-rational design and screening of mutant libraries in recombinant Escherichia coli cells;Methods in Enzymology;2023

4. Opportunities for Accelerating Drug Discovery and Development by Using Engineered Drug-Metabolizing Enzymes;Drug Metabolism and Disposition;2022-12-02

5. Current state and future perspectives of cytochrome P450 enzymes for C–H and C=C oxygenation;Synthetic and Systems Biotechnology;2022-09

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