Modeling the pharmacokinetic‐pharmacodynamic relationship of the monoclonal anti‐macaque‐ IL ‐15 antibody Hu714Mu XH u in cynomolgus monkeys-Reference-Cited by-同舟云学术

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Modeling the pharmacokinetic‐pharmacodynamic relationship of the monoclonal anti‐macaque‐ IL ‐15 antibody Hu714Mu XH u in cynomolgus monkeys

Published:2015-12 Issue:6 Volume:3 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

Pan Wei. J.¹,Li Hong¹,Xiao Jim J.²,Horner Michelle J.³,Lebrec Herve N.⁴,Butz Eric A.⁵,Kaliyaperumal Arunan⁶,Cheah Tsui C.²,Ortiz Robert C.²,Prokop Samantha P.¹,Buntich Sabina A.³,Boren Babette M.⁴,Wolford Suzanne T.⁷,Tsuji Wayne H.⁸,Wienkers Larry C.¹,Köck Kathleen¹

Affiliation:

1. Pharmacokinetics and Drug Metabolism Amgen Inc. Seattle Washington

2. Pharmacokinetics and Drug Metabolism Amgen Inc. Thousand Oaks Washington

3. Comparative Biology and Safety Sciences Amgen Inc. Thousand Oaks California

4. Comparative Biology and Safety Sciences Amgen Inc. Seattle Washington

5. Inflammation Discovery Research Amgen Inc. Seattle Washington

6. Medical Sciences Amgen Inc. Thousand Oaks California

7. Covance Laboratories Inc. Madison Wisconsin

8. Medical Sciences Amgen Inc. Seattle Washington

Funder

Amgen

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.199

Reference37 articles.

1. IL-15: a central regulator of celiac disease immunopathology

2. IL-15 and IL-15R in leucocytes from patients with systemic lupus erythematosus

3. Inhibition of TGF-β Signaling by IL-15: A New Role for IL-15 in the Loss of Immune Homeostasis in Celiac Disease

4. Immunosuppression by the JAK3 Inhibitor CP-690,550 Delays Rejection and Significantly Prolongs Kidney Allograft Survival in Nonhuman Primates

5. Are Population Pharmacokinetic and/or Pharmacodynamic Models Adequately Evaluated?

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Counteracting Interleukin-15 to Elucidate Its Modes of Action in Physiology and Pathology;Journal of Interferon & Cytokine Research;2023-01-01

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