In Silico Design and SAR Study of Dibenzyl Trisulfide Analogues for Improved CYP1A1 Inhibition
Author:
Affiliation:
1. Phillips Academy 180 Main Street Andover MA-01810 USA
2. Natural Products Institute University of the West Indies Mona Kingston 7 Jamaica
Publisher
Wiley
Subject
General Chemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/open.202200016
Reference43 articles.
1. Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2. Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and1B1
3. Human Drug-Metabolizing Enzyme Polymorphisms: Effects on Risk of Toxicity and Cancer
4. Role of Aryl Hydrocarbon Receptor-mediated Induction of the CYP1 Enzymes in Environmental Toxicity and Cancer
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