Affiliation:
1. LAQV@REQUIMTE Departamento de Química NOVA School of Science and Technology Universidade Nova de Lisboa Campus de Caparica 2829-516 Caparica Portugal
2. LAQV@REQUIMTE Department of Chemistry University of Aveiro 3810-193 Aveiro Portugal
Abstract
AbstractThe indole moiety is an important N‐heterocycle found in natural products, and a key structural component of many value‐added chemicals including pharmaceuticals. In particular, bis(3‐indolyl)methanes (BIMs) are an important subgroup of indoles, composed of two indole units. Herein, we report the development of a simple method to access BIMs derivatives in yields of up to 77 % by exploiting a tBuOK‐mediated coupling reaction of indoles and benzyl alcohols.
Cited by
6 articles.
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