Prediction of Human Pharmacokinetics and Pharmacodynamics
Author:
Affiliation:
1. Vertex Pharmaceuticals; Department of Modeling and Simulation; 50 Northern Avenue Boston MA 02210 USA
Publisher
Wiley-VCH Verlag GmbH & Co. KGaA
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/9783527801756.ch15/fullpdf
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2. Early integration of pharmacokinetic and dynamic reasoning is essential for optimal development of lead compounds: strategic considerations;Gabrielsson;Drug Discov. Today,2009
3. Quantitative pharmacology or pharmacokinetic pharmacodynamic integration should be a vital component in integrative pharmacology;Gabrielsson;J. Pharmacol. Exp. Ther.,2009
4. Optimizing DMPK properties: experiences from a big pharma DMPK department;Sohlenius-Sternbeck;Curr. Drug Metab.,2016
5. Comprehensive assessment of human pharmacokinetic prediction based on in vivo animal pharmacokinetic data, Part 1: volume of distribution at steady state;Lombardo;J. Clin. Pharmacol.,2013
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