Discovery and Development of Obinutuzumab (GAZYVA, GAZYVARO), a Glycoengineered Type II Anti-CD20 Antibody for the Treatment of Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia

Author:

Klein Christian1,Mössner Ekkehard1,Bacac Marina1,Fingerle-Rowson Günter2,Umaña Pablo1

Affiliation:

1. Roche Pharmaceutical Research and Early Development; Roche Innovation Center Zurich; Wagistrasse 10 CH-8952 Schlieren Switzerland

2. Pharma Development Oncology; F. Hoffmann-La Roche; Basel Switzerland

Publisher

Wiley-VCH Verlag GmbH & Co. KGaA

Reference109 articles.

1. Newly diagnosed and relapsed follicular lymphoma: ESMO clinical practice guidelines for diagnosis, treatment and follow-up;Dreyling;Ann. Oncol.,2016

2. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) 2017a Non-Hodgkin Lymphoma, Version 4 http://www.nccn.org/professionals/physician_gls/f_guidelines.asp#site

3. Diffuse large B-cell lymphoma (DLBCL): ESMO clinical practice guidelines for diagnosis, treatment and follow-up;Tilly;Ann. Oncol.,2015

4. Chronic lymphocytic leukaemia: ESMO clinical practice guidelines for diagnosis, treatment and follow-up;Eichhorst;Ann. Oncol.,2015

5. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) 2017b Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 1 http://www.nccn.org/professionals/physician_gls/f_guidelines.asp#site

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