Affiliation:
1. College of Pharmacy Rungsit University Pathum Thani Thailand
2. Central Chest Institute of Thailand Nonthaburi Thailand
3. Clinical Pharmacy Division, Department of Pharmacy, Faculty of Pharmacy Mahidol University Bangkok Thailand
4. Faculty of Pharmacy Siam University Bangkok Thailand
Abstract
AbstractBackgroundAlthough significant advancements have been made in the acute management of acute coronary syndrome (ACS) in Thailand, there is a need for improvement in the longitudinal care post cardiac stenting.ObjectiveThe study aimed to describe the successful establishment of the first post‐percutaneous coronary intervention (PCI) clinic in Thailand and its preliminary impact compared with historical controls.MethodA multidisciplinary outpatient clinic entitled the “post‐PCI clinic,” consisting of cardiologists, nurses, clinical pharmacists, a physical therapist, and a dietitian, was established in 2016 to provide longitudinal care for patients who underwent cardiac stenting at a tertiary care hospital. A standard care pathway, along with the clinic's standard operating protocols, was designed and implemented. A pre‐post intervention, quasi‐experimental study, was conducted to compare the usage rate of secondary prevention medications between patients enrolled in the post‐PCI clinic (January–April 2016) and historical controls (January–June 2015) at month 6 after hospital discharge.ResultsDuring January–April 2016, 91 patients were enrolled in the post‐PCI clinic, with a mean age of 59.2 ± 11.9 years and 65.9% being male. Of these patients, 94.5% presented with ST‐segment elevation myocardial infarction. Regarding the PCI procedure, 90.1% underwent primary PCI, and 9.9% underwent elective PCI. Almost all patients (98.9%) received drug‐eluting stent placement, except for one. Compared with the historical control group, the usage rates of Angiotensin‐converting enzyme (ACE) inhibitors/Angiotensin Receptor Blockers (ACEIs/ARBs) (94.5% vs. 76.5%; p < 0.001), beta‐blockers (93.4% vs. 81.4%; p = 0.013), and high‐intensity statins (90.1% vs. 33.3%; p < 0.001) were higher in the post‐PCI clinic group 6 months after discharge. The three most common interventions by clinical pharmacists were recommendations to initiate new therapy (52.4%), suggestions to adjust dosage regimen (36.7%) and suggestions to change therapy (10.9%).ConclusionThe post‐PCI clinic led to a higher usage rate of secondary prevention medications compared with historical controls.
Reference30 articles.
1. Epidemiology and the magnitude of coronary artery disease and acute coronary syndrome: a narrative review;Ralapanawa U;J Epidemiol Glob Health,2021
2. A global overview of acute coronary syndrome registries: a systematic review;Nabovati E;Curr Probl Cardiol,2023
3. Division of Non Communicable Disease Department of Disease Control Ministry of Public Health.NCD report 2019: Diabetes Hypertension and risk factors. Ministry of Public Health Thailand.2019.
4. Thai Acute Coronary Syndrome Registry.https://www.ncvdt.org/Default.aspx
5. Demographic, management practices and in‐hospital outcomes of Thai acute coronary syndrome registry (TACSR): the difference from the Western world;Srimahachota S;J Med Assoc Thai,2007