Development and validation of a gas chromatography/tandem mass spectrometry method for simultaneous quantitation of several antipsychotics in human plasma and oral fluid

Author:

Rosado Tiago12,Oppolzer David1,Cruz Belinda1,Barroso Mário3,Varela Samira4,Oliveira Victor4,Leitão Carlos4,Gallardo Eugenia12ORCID

Affiliation:

1. Centro de Investigação em Ciências da Saúde; Universidade da Beira Interior (CICS-UBI); Covilhã Portugal

2. Laboratório de Fármaco-Toxicologia-UBIMedical; Universidade da Beira Interior; Covilhã Portugal

3. Serviço de Química e Toxicologia Forenses; Instituto Nacional de Medicina Legal e Ciências Forenses; Delegação do Sul Lisboa Portugal

4. Centro Hospitalar Cova da Beira, E.P.E; Departamento de Psiquiatria e Saúde Mental; Covilhã Portugal

Funder

FEDER funds through the POCI - COMPETE 2020 - Operational Programme Competitiveness and Internationalisation in Axis I-Strengthening research, technological development and innovation

Fundação para a Ciência e a Tecnologia

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference74 articles.

1. World Health Organization. Schizophrenia and public health 1998 http://www.who.int/mental_health/media/en/55.pdf

2. The evolution of drug development in schizophrenia: Past issues and future opportunities;Carpenter;Neuropsychopharmacology,2008

3. Schizophrenia: Overview and treatment options;Patel;Pharm Therapeut,2014

4. Correlation of haloperidol levels between saliva and plasma of acutely ill schizophrenic patients;Jain;Clin Biochem,2011

5. Bioanalytical methods for the determination of antipsychotic drugs;Zhang;Biomed Chromatogr,2008

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